Principal Investigator |
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Zhenglong GuProfessor |
Current Lab Members |
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Xiaoxian GuoPostdoctoral Associate (2013- ) |
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Tianyi ZhangPostdoctoral Associate (2016- ) My research mainly focuses on the TP53 and MTHFR genes in humans, which are sensitive to stress signals, especially temperature. Their various single-nucleotide polymorphisms may lead to different responses in different environments. Utilizing DNA editing technologies, our goal is to develop in vitro models with TP53 and MTHFR mutations respectively, and explore the relationship between these mutations and temperature adaptation. Our work also includes developing effective DNA editing methods for mammalian mitochondrial DNA. |
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Lingfeng TangPostdoctoral Associate (2016- ) I am interested in the functions of mitochondria in oogenesis. |
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Xuan YangPostdoctoral Associate (2018- ) |
Shaohuan WuPostdoctoral Associate (2018- ) |
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Inna SirotaGraduate Student I am interested in the role of mitochondrial DNA (mtDNA) in cancer. Specifically, I am interested in the effects of mtDNA heteroplasmy on the cancer phenotype and drug response. Another approach that I am taking to define the role of mtDNA in cancer is through the cybrid model. The cybrid model is the fusion of an enucleated cell with a cell without mtDNA, so that there is a nucleus from one cell and mtDNA from another. Through both of these approaches, we hope to better understand the influence of mitochondrial function on the cancer phenotype. |
Yiqin WangGraduate Student |
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Yiping WangGraduate Student |
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Yuanyuan WuGraduate Student (2017- ) |
Weilin XuGraduate Student (2018-) |
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Troy AndersonUndergraduate Research Student (2017- ) |
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Andrew Mingtai CheungUndergraduate Research Student (2017- ) |
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Fiona ChuUndergraduate Research Student (2017- ) |
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Yihua WuUndergraduate Research Student (2017- ) |
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Yibing (Shirley) YaoUndergraduate Research Student (2017- ) |
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Reena OlsenUndergraduate Research Student (2018- ) |
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Megha SinghUndergraduate Research Student (2018- ) |
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Jonathan ChaiUndergraduate Research Student (2018- ) |
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Emine OzenUndergraduate Research Student (2018- ) |
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Diego Antonio JimenezUndergraduate Research Student (2018- ) |
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Izzie FanUndergraduate Research Student (2018- ) |
Past Lab Members |
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Elizabeth HermanUndergraduate Research Student (2016-2018) |
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Susie ChunUndergraduate Research Student (2017-2018) |
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Daniel LeeUndergraduate Research Student (2018-2018) |
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Julia JeongUndergraduate Research Student (2017-2018) |
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Yuan SiGraduate Student (2013-2018) Current position: Licensing Fellow | Innovation Gateway Office of Research | University of Georgia |
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Josephine WeePostdoctoral Associate Current position: Assistant Professor at The Pennsylvania State University |
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Ruoyu ZhangGraduate Student (2013-2018) Current position: Associated scientist, bioinformatics Regeneron Pharmaceuticals |
Jenelle Antonia BonnerUndergraduate Student |
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Paul Billing-RossMaster Student (2013-2018) Current position: Bioinformatics Software Developer at Stanford University School of Medicine |
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Kaixiong YeGraduate Student Current position: Assistant Professor at University of Georgia |
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Zhe WangPostdoc |
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Brandon BarkerGraduate Student |
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Hong ChenGraduate Student (2007-2012) Current position: Senior Scientist, High Throughput Screening Core, UT Southwestern Medical Center |
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Lin XuGraduate Student (2006-2012) Current position: Assistant Professor at UT Southwestern Medical |
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Huifeng JiangPostdoc (2008-2012) Current position: PI, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences |
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Jonathan BurrisUndergraduate Research Student |
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Faraz ButteUndergraduate Research Student |
Roberto FloresLab Manager (2009-2010) Current Status: Ph.D. of Biology, The Department of Biology, Boston College |
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Michael ZettelLab Manager (2006) | |
